Increasing Bioefficacy in Cosmetic Formulations

In addition to claims substantiation testing, AMA Laboratories Inc. performs efficacy and safety testing on a variety of consumer products. AMA Laboratories Inc. works with many clients in the cosmetics and personal care sector, helping them to establish the best formulations to achieve their goals.

A primary driver of the claims made about cosmetics is bio-active compounds in the formulation. Therefore, it’s crucial to make those compounds as efficacious as possible. The first step to maximizing efficacy is to understand the biological mechanism that the product is trying to modify. Skin lightening, for instance, will be closely tied to melanin synthesis.

Once the mechanism is identified, you can move on to finding the best ingredients to act on that mechanism. It will probably take substantial experimentation to find the right ingredient that will be best suited for every process in the mechanism.

Then, once all the most effective ingredients are identified, you’ll need to make sure there’s a stable formulation possible with their combination. This will involve considerable testing to find a formulation with an acceptable shelf life. This can be accelerated through various means.

Once that work is done, you can move on to the final determination which, of course, involves clinical testing. If you’ve done the due diligence correctly throughout the process this final stage shouldn’t be a problem, and the product should perform as intended.

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